Developing medicines for neurological diseases
shaped by the distinct cycles of women’s biology.

It just never shaped how we treat it. Estrogen and progesterone are key regulators of many disease pathways including neurological, autoimmune, and cardiovascular, yet most medicines are developed without accounting for the effects of fluctuating hormones throughout the female lifespan. Their influence can be seen across disease prevalence, clinical presentation and progression, treatment response, and side effects.

Songbird’s initial focus is on neurological disorders affected by estrogen and progesterone. Below are some of the organ systems where disorders are known to be shaped by hormonal biology.